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    <title>Zero Brane</title>
    <link>http://notebook.kulchenko.com/</link>
    <description>By seeking, you will discover...</description>
    <language>en</language>
    <copyright>Copyright 2009</copyright>
    <lastBuildDate>Sat, 03 Dec 2005 07:13:26 GMT</lastBuildDate>
    <pubDate>Sat, 03 Dec 2005 07:13:26 GMT</pubDate>
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    <title>Neural Modeling: Neuron</title>
    <description>&lt;p&gt;It seems logical to &lt;a href="modeling/neural-modeling"&gt;start building a neural network framework or a simulator&lt;/a&gt; with a neuronal model. Neuronal models and their implementations range from simple (like the &lt;a href="http://www.btinternet.com/~cfinnie/model.html"&gt;model that is implemented in Neural Viewer&lt;/a&gt;) to very complex (like the Hodgkin-Huxley model). While there are many models to use (&lt;a href="references/papers/which-model-to-use"&gt;Which model to use for cortical spiking neurons?&lt;/a&gt; article provides a good coverage of the existing models) I like the model proposed by Eugene Izhikevich in &lt;a href="references/papers/simple-model-of-spiking-neurons"&gt;Simple model of Spiking Neurons&lt;/a&gt; as it is computationally efficient and still biologically plausible.&lt;/p&gt;

&lt;p&gt;Eugene's website provides &lt;a href="http://www.nsi.edu/users/izhikevich/publications/figure1.m"&gt;&lt;span class="caps"&gt;MATLAB &lt;/span&gt;scripts&lt;/a&gt; to play with the models, but since I didn't have access to a &lt;span class="caps"&gt;MATLAB &lt;/span&gt;instance I decided to reproduce the same set of diagrams using Perl. After a couple of weeks of experiments and several emails to the author I was able to model various types of neurons according to the parameters described in &lt;a href="references/books/dynamical-systems-in-neuroscience"&gt;Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting&lt;/a&gt;. Here is how the results look for the &lt;strong&gt;regular spiking (RS)&lt;/strong&gt; neuron:&lt;/p&gt;

&lt;p&gt;&lt;img src="/images/neuron-izh-rs.gif" alt="" /&gt;&lt;/p&gt;

&lt;p&gt;And here are the results for the &lt;strong&gt;chattering (CH)&lt;/strong&gt; neuron:&lt;/p&gt;

&lt;p&gt;&lt;img src="/images/neuron-izh-ch.gif" alt="" /&gt;&lt;/p&gt;</description>
    <guid>http://notebook.kulchenko.com/modeling/neural-modeling-neuron</guid>
    <category>modeling/</category>
    <pubDate>Sat, 03 Dec 2005 07:13:26 GMT</pubDate>
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