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  <title>Zero Brane</title>
  <link>http://notebook.kulchenko.com/</link>
  <description>By seeking, you will discover...</description>
  <dc:language>en</dc:language>
  <dc:creator>Paul Kulchenko</dc:creator>
  <dc:date>2005-12-25T07:17:47Z</dc:date>
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    <title>Neural Modeling: Synaptic Plasticity</title>
    <link>http://notebook.kulchenko.com/modeling/neural-modeling-synaptic-plasticity</link>
    <description>&lt;p&gt;Reviewing the code of the &lt;a href="modeling/neural-modeling-spnetplusplus"&gt;&lt;span class="caps"&gt;SPN&lt;/span&gt;et++&lt;/a&gt; I realized that the implemented synaptic plasticity mechanism in the simulation is much simpler than I expected. It turned our that the code implements the nearest-neighbor spike model described in &lt;a href="references/papers/relating-stdp-to-bcm"&gt;&lt;span class="caps"&gt;RELATING&lt;/span&gt;-STDP-TO-BCM&lt;/a&gt; article by Eugene M. Izhikevich and Niraj S. Desai. According to the authors of the article &lt;em&gt;it may be sufficient to only consider two postsynaptic spikes&lt;/em&gt; -- the one that occurs before and the one that occurs after the presynaptic firing -- while determining whether a synapse should be potentiated or depressed based on recent spike activity. In addition to attempting to unify different forms of plasticity -- spike-timing-dependent plasticity (STDP) and a standard long-term potentiation and depression (LTP/LTD) -- into a single framework, this approach appears to be very computationally efficient.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;update 2006/01/14&lt;/strong&gt;: &lt;a href="references/papers/STDP-based-on-local-information"&gt;&lt;span class="caps"&gt;STDP&lt;/span&gt;-BASED-ON-LOCAL-INFORMATION&lt;/a&gt; paper presents an alternative rule, which is also described as computationally efficient, yet simple and reliable. This paper also provides five types of gating functions: no gating, presynaptic, postsynaptic, dual OR and dual &lt;span class="caps"&gt;AND &lt;/span&gt;gating.&lt;/p&gt;

&lt;p&gt;There is also more information on different types of synaptic plasticity in the post on &lt;a href="modeling/neural-modeling-synaptic-connectivity"&gt;synaptic connectivity&lt;/a&gt;.&lt;/p&gt;</description>
    <dc:subject>modeling/</dc:subject>
    <dc:date>2005-12-25T07:17:47Z</dc:date>
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